Restless Legs Syndrome Support Group – DailyStrength:

“All people with RLS should have their ferritin levels tested; ferritin levels should be at least 50 mcg for those with RLS. Oral iron supplements, taken under a doctor’s care, can increase ferritin levels. For some people, increasing ferritin will eliminate or reduce RLS symptoms. At least 40% of people will not notice any improvement, however. IV iron is being tested at the US Mayo Clinic as a method of treating RLS. It is dangerous to take iron supplements without first having ferritin levels tested, as many people with RLS do not have low ferritin and excess iron in the body can cause hemochromatosis, a very dangerous condition.”